A POSSIBLE RELATIONSHIP OF VITAMIN B13 TO OROTIC ACID

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A possible relationship of vitamin B13 to orotic acid.

Novak, Hauge, and Carrick (1) presented evidence that one or more unidentified chick growth factors were present in distillers’ dried solubles (DDS). Novak and Hauge (2) announced the isolation of an unknown growth factor in a relatively high degree of purity from DDS. This substance was very potent in stimulating rat growth and was designated vitamin B13. It has an ultraviolet absorption maxim...

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Orotic acid in milk.

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Orotic Acid Feeding

1. The metabolism of 4-[4-14C]androstene-3,17-dione, 4-[4-14C]pregnene-3,20-dione, 5a-[4-14C]androstane-3a,17f8-diol, [4-4C]cholesterol, 7a-hydroxy4-6fi-3H]cholesten3-one, 5fi-[7fi-3H]cholestane-3a,7U-diol and [3H]lithocholic acid was studied in the microsomal fraction of livers from control and orotic acid-treated male rats. 2. As a result of the treatment the orotic acid-fed rats had fatty li...

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A relationship of vitamin E to nucleic acid metabolism.

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Redetermination of orotic acid monohydrate

The crystal structure of the title compound, which is also known as vitamin B(13) (systematic name: 2,6-dioxo-1,2,3,6-tetra-hydro-pyrimidine-4-carboxylic acid monohydrate), C(5)H(4)N(2)O(4)·H(2)O, was reported for the first time by Takusagawa & Shimada [Bull. Chem. Soc. Jpn (1973 ▶), 46, 2011-2019]. The present redetermination provides more precise values of the mol-ecular geometry. The asymmet...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1953

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(19)57110-1